Medical Science Liaison - Pipeline, Immunology (California)

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can change the course of medicine and bring big new ideas to life. As an Immunology Pipeline MSL, you’ll play a pivotal role in advancing our science to bring life-changing medicines to patients.  

AstraZeneca has a broad and deep pipeline of next-generation medicines in Immunology.  We are seeking highly motivated and experienced individuals to support scientific dialogue, drive clinical trial engagement and foster collaborations across AstraZeneca’s immunology pipeline. Your work will facilitate the running of current and future clinical programs across multiple autoimmune disease areas with a focus on rheumatology and gastroenterology.  

The Immunology Pipeline MSL is a field-based professional with scientific, clinical and therapeutic area expertise, responsible for building external relationships with identified and emerging health care providers and investigators and providing scientific and clinical trial support to advance AstraZeneca’s immunology pipeline. You will be working closely with global and country R&D teams, as well as medical affairs teams working on established products, to ensure strategic, cohesive account engagement and a unified external presence. 

Must live in the territory or following cites/states: Los Angeles, San Diego, San Francisco, CA

Key Responsibilities 

​Scientific engagement and relationship building: 

• Deliver enhanced scientific and medical exchange at the portfolio-level, including Cell Therapy, T cell engagers and other novel immunomodulatory monoclonal antibodies and small molecules 

• Build strong, non-promotional relationships with investigators, study staff and referring HCPs at investigational sites and key scientific centers to support active and planned AZ-sponsored immunology trials.  

• Identify stakeholders and opportunities for engagement and collaborations with R&D and medical affairs  

• Educate clinical trial sites and referring physicians on AZ’s immunology portfolio and study designs to enhance understanding of objectives and drive clarity in patient identification across multiple AZ studies.  

Site strategy, feasibility and trial enrolment:  

• Map and engage disease, community, and investigator networks; identify new sites and referral pathways.  

• Support feasibility by assessing patient pools, standard-of-care patterns, competing trials and operational capabilities.  

• Obtain, synthesize and share insights with R&D to inform protocol design, site strategy, and recruitment tactics. 

• In collaboration with Site Management and Monitoring (SMM), proactively explore enrolment and screening barriers and support clinical trial recruitment and retention; collaborate with clinical operations to identify and facilitate resolution of investigator site issues. 

Essential Requirements 

• Advanced degree in a scientific discipline e.g., MD, DO, PharmD, PhD, NP, PA-C. 

• Minimum of 2 years field medical experience e.g. MSL or Clinical Trial Liaison role and/or minimum of 2 years clinical trial research experience within an academic, healthcare system or industry setting. 

• Demonstrated excellence in scientific communication across different audiences. Proficiency in developing and maintaining medical scientific expertise. 

• Thorough knowledge of regulatory environment 

• Ability to travel 50–70% of the time (percentage varies with geography). 

Desirable Requirements 

• Experience in rheumatology, gastroenterology or neurology 

• Experience with clinical research and study site logistics, including GCP/ICH familiarity 

• Experience in pharmaceutical industry, regulatory environment, clinical or preclinical research 

• Entrepreneurial and future-forward mindset, with demonstrated ability to build advocates and momentum in complex trial ecosystems. 

• Track record of successful network building or shaping treatment environment 

• Experience mapping disease/community networks and facilitating patient referrals through advocacy connectivity 

Why AstraZeneca: Here, patient needs drive our decisions and fuel our courage to innovate. You will work with unexpected teams that combine diverse perspectives to deliver evidence-based materials that influence care for people living with rare and devastating diseases. We balance the energy of a nimble biotech mindset with the scale and resources of a global biopharma, pairing cutting-edge science with a culture that values kindness alongside ambition. Your expertise will shape how clinicians understand our medicines, and you will grow in a community that supports honest debate, cross-functional collaboration, and meaningful impact.