United States
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Remote · United States
Remote · United States
Camp Lejeune, United States
San Diego, United States
Pay not published. Too few similar jobs show pay for a fair estimate.
Position Purpose
The Pfizer Inflammation & Immunology Research Unit (I&I RU) in Cambridge, MA, is seeking an experienced Principal Scientist (R5) to join the in vivo pharmacology group as a subject matter expert and scientific leader.
In this senior role, you will lead the preclinical in vivo pharmacology strategy focused on neuroinflammatory mechanisms in Alzheimer’s disease and related neurodegenerative disorders. You will serve as both a conceptual driver and a technical authority—responsible for designing, directing, and critically interpreting in vivo, ex vivo, and complementary in vitro studies that elucidate disease biology and establish target engagement, pharmacodynamics, and therapeutic efficacy.
Beyond core study design, you will spearhead the establishment of next-generation mouse models and advanced behavioral and physiological endpoints, lead cross-functional drug discovery project teams, mentor scientific staff, and champion innovative scientific avenues to fuel Pfizer’s preclinical neurodegeneration and neuroinflammation pipeline.
This position offers an opportunity to drive impactful research in neuroinflammation while collaborating closely with multidisciplinary project teams to advance therapeutic discovery.
Primary Responsibilities
Technical and Scientific Requirements
Qualifications:
PHYSICAL/MENTAL REQUIREMENTS
Ability of lifting, sitting and standing for prolonged time required.
Additional Information:
The annual base salary for this position ranges from $106,000.00 to $176,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development