Job Title: Head, US E-Commerce
About the Job
The Head, E-Commerce is a senior commercial leader within a commercial Business Unit in a health care company and responsible for defining and driving the strategic direction of the company’s B2B digital commerce platform. This role operates at the intersection of business strategy, customer experience, and digital capability—translating complex market dynamics into a clear, actionable e-commerce vision that delivers measurable growth.
Sitting within the Commercial organization and reporting to the Vice President, this leader commands visibility at the SVP and business unit head levels, and engages senior leadership as a thought partner on digital commerce transformation. This leader interacts closely with the Digital E-Commerce organization—co-owning the platform roadmap, shaping priorities, and influencing execution—while retaining full accountability for the commercial strategy and e-commerce business outcomes.
The ideal candidate has extensive hands-on B2B commercial experience and demonstrated sales growth, in healthcare or specialty distribution, medical devices, diagnostics, or other sectors where supply chains and relationship-driven selling intersect with digital channel growth. They are equally at home synthesizing market intelligence into strategic frameworks and driving cross-functional teams toward concrete results as well as understanding the tech stack. The ideal candidate has management consulting experience (2-4 years). Above all, this leader is obsessed with the driving e-commerce growth — through retention, deepening relationships, accelerating growth, operational excellence, and identifying the next wave of innovation in B2B digital commerce.
Our organization in North America Vaccines is growing fast, and we're always looking for talented professionals to join our Commercial Operations’ team.
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.
Why join our team?
Our Commercial Operations team aims for excellence. We offer a diverse and dynamic environment that’s growing at pace.
The Head, E-Commerce is a senior commercial leader within a commercial Business Unit in a health care company and responsible for defining and driving the strategic direction of the company’s B2B digital commerce platform. This role operates at the intersection of business strategy, customer experience, and digital capability—translating complex market dynamics into a clear, actionable e-commerce vision that delivers measurable growth.
Sitting within the Commercial organization and reporting to the Vice President, this leader commands visibility at the SVP and business unit head levels, and engages senior leadership as a thought partner on digital commerce transformation. This leader interacts closely with the Digital E-Commerce organization—co-owning the platform roadmap, shaping priorities, and influencing execution—while retaining full accountability for the commercial strategy and e-commerce business outcomes.
The ideal candidate has extensive hands-on B2B commercial experience and demonstrated sales growth, in healthcare or specialty distribution, medical devices, diagnostics, or other sectors where supply chains and relationship-driven selling intersect with digital channel growth. They are equally at home synthesizing market intelligence into strategic frameworks and driving cross-functional teams toward concrete results as well as understanding the tech stack. The ideal candidate has management consulting experience (2-4 years). Above all, this leader is obsessed with the driving e-commerce growth — through retention, deepening relationships, accelerating growth, operational excellence, and identifying the next wave of innovation in B2B digital commerce.
Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you'll help advance prevention on a global scale - and shape the future of immunization. Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.
About Sanofi
We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.
Main Responsibilities
Commercial E-Commerce Strategy & Vision
Own the end-to-end B2B US e-commerce commercial strategy, defining the vision, priorities, and multi-year roadmap that drives customer acquisition, retention, and revenue growth.
Translate macro trends, competitive dynamics, and customer insights into differentiated strategic positions; build the business case for investment and present recommendations to VP, SVP, and business unit head-level stakeholders.
Customer Retention, Growth & Experience
Develop and oversee e-commerce strategies targeted at deepening existing customer relationships and reducing churn, with a particular focus on healthcare providers, institutional buyers, and other B2B account segments.
Define and monitor key performance indicators (KPIs) for platform adoption, customer engagement, digital revenue contribution, and retention; hold the organization accountable to outcomes.
Innovation & Market Intelligence
Maintain a continuous pulse on emerging B2B e-commerce trends, competitive moves, and adjacent industry practices (particularly in healthcare and life sciences); translate insights into strategic recommendations.
Roadmap Co-Ownership & Digital Partnership
Partner with the Digital E-Commerce organization as a co-owner of the platform roadmap, ensuring business priorities are clearly articulated, sequenced, and reflected in technology delivery plans.
Cross-Functional Leadership & Stakeholder Engagement
Lead and develop a team of e-commerce professionals in the commercial team, fostering a high-performance culture grounded in strategic thinking, analytical rigor, and customer centricity, and focus on their career development.
Build and maintain strong relationships across Commercial, Digital, Marketing, Customer Experience, Legal, Finance to ensure alignment and remove barriers to execution.
About You
Education & Experience
Demonstrated experience leading B2B e-commerce strategy and/or digital channel development, ideally in a complex, multi-stakeholder environment, demonstrating success in driving sales growth
Industry experience in healthcare, life sciences, medical devices, diagnostics, specialty distribution, or other B2B sectors involved in direct supply chain; experience in regulated or relationship-intensive industries valued
Bachelor’s degree required; MBA or advanced degree strongly preferred, particularly from a top-tier institution with a focus in business strategy, marketing, or a related field.
10+ years of progressive experience, with meaningful depth in B2B e-commerce strategy, digital channel development, or digital marketing in a complex commercial environment.
Knowledge & Skills
Strategic Thinking & Synthesis: Structures ambiguous problems, synthesizes complex data and market dynamics, and delivers clear, compelling recommendations (a consulting-trained mindset)
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Work at the forefront of AI-driven research, smart manufacturing, and groundbreaking mRNA platforms that are redefining the future of immunology.
Help protect half a billion people every year, contributing to one of the largest global vaccination efforts in healthcare.
Develop your career with access to mentoring, international mobility programs, and opportunities to grow across four continents.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
#GD-SP
#LI-GP
#LI-Hybrid
#vhd
Pursue
progress, discover
extraordinaryBetter is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
Sanofi US endeavours to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-866-SANOFI2 (1-866-726-6342) or click here
US and Puerto Rico Residents Only
Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
North America Applicants Only
The salary range for this position is:
$187,500.00 - $270,833.33
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.