The Manufacturing Science and Technology (MSAT) function at GSK’s Irvine manufacturing site provides technical expertise in the industrial application of science, innovative technology and process to ensure that Drug Substances and Drug Products are understood and their product performance is enhanced throughout their product life cycle. MSAT entails all elements of the manufacture, testing and supply process.
Job Purpose:
The Digital and Technology Lead drives the adoption of industry recognised Digital and Technology solutions across the Irvine site to ensure optimum performance and automated-corrective responses are in place. The aim is to ensure that technology is in place to measure process performance, provide deep data analysis and drive embedding solutions (including optimizing in-process controls).
This role encompasses the full manufacturing and supporting processes across the site (from simplifying technical transfer of Fermentation Strain - predictive scale-up - to highlighting purification performance improvements) through deep data analysis and leaning on process modelling to limit local experiments and simplify implementation of process change. You will programme manage the implementation of technological solutions to drive process productivity and seek transformational change of established production processes.
Key Responsibilities (include..,):
• Act as voice of the customer on behalf of MSAT using and re-using data and evolving knowledge, capturing requirements and needs for building Product data and knowledge
• Provide a high level of technical expertise to site in the supply of data to support the standardisation, visualization, and improvement of business processes for Product Lifecycle Management including Continuous Process Verification, stability, validation, investigations, TRA, RCA, Product Performance Assessment (PPA), Continuous Improvement and Data Stewardship, as applied to manufacturing operations
• Define the business processes and associated benefits for use of data, information and analytics. Link these to the site aims and escalate projects to fill any gaps
• Keep up to date with technologies and capabilities that utilise data and information to ensure the appropriate solutions are utilised to maximise business benefits
• Drive programmes of work for Fermentation productivity improvement by leveraging on latest technology and data capture/transfer
• Identify digital solutions for data capture and analysis – e.g. equipment cleaning validation and positive confirmation of standards adhered to
• Drive the use of digital by first intent through process modelling (e.g. mechanistic and empirical) and engage Global MSAT statistics and modelling teams for support
About You:
This role would suit a self-motivated person who has experience of working in a cross-functional, global supply organisation. You will have strong people-management skills, including a proven ability to influence people to achieve goals (as you will work closely with a wide range of teams, colleagues, senior-stakeholders). You will also have a strong continuous improvement mindset. Knowledge and previous interaction with Global MSAT and other support functions would be advantageous.
CLOSING DATE for applications: Monday 19th of October 2026 (COB).
Basic Qualifications:
- Relevant degree (eg; Scientific, Technical or Engineering) or strong relevant experience.
- Relevant working experience in delivery of technical standards / solutions with proven application (eg; data-analysis and optimisation, or validation and change management, or product and process optimisation, process modelling, etc).
- Evidence of managing improvement projects in a matrix environment
If you would like to learn more about our company wide benefits and life at GSK we would suggest looking at our webpage Life at GSK | GSK.
Skills
CMC Strategy, Data-Driven Decision Making, Data Integrity, Debate Moderation, Digital Fluency, GxP Regulations, Lean Management, Problem Solving, Process Optimization, Project Leadership, Risk Awareness, Scientific Writing, Technology Transfer
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
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