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On-siteFull-timeEntry level
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Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world.
As a Bioinformatics Technologist I or II, you will develop, maintain and run software systems and bioinformatic pipelines for processing and analyzing next-generation sequencing data. In this role, you will perform software programming in various languages, including raw data quality control, sequence alignment, variant calling, annotation and reporting. You will provide input to develop software and data analysis solutions, complete department tasks and provide ongoing support for existing databases and software while working collaboratively with software engineers, computational biologists, and clinical and basic research scientists.
This role will participate in translational cancer research. The laboratory of Dr. Przybyl develops novel, clinically applicable liquid biopsy testing methods for sarcoma and applies multi-omic (genomic, transcriptomic, proteomic and methylome) high-throughput methods to discover new diagnostic markers and therapeutic targets in sarcomas. In this role, you will build bioinformatic pipelines, analyze high-throughput data and interpret results using statistical techniques. You will also develop and implement data analyses, acquire data from primary or secondary data sources and maintain databases.
We will hire our Bioinformatics Technologist in two different job titles, based on educational background:
Bioinformatics Technologist
Bioinformatics Technologist II
A caregiver in this role works days from 8:00 a.m. -- 5:00 p.m.
A caregiver who excels in this role will:
Assist with testing hypotheses and designing studies and recommending analytical strategies.
Develop basic statistical, mathematical and predictive models, build algorithms and perform data analytics.
In collaboration with bioinformatics specialists, maintain and run software systems for bioinformatics processing of sequence data, including raw data quality control, sequence alignment, variant calling, annotation and reporting.
Develop and implement workflows for data analysis tools in collaboration with research scientists.
Build and deploy data analysis support systems for large datasets, including well-structured flat files, APIs and other types of services.
Acquire, clean, structure and manage data from multiple sources to ensure data quality.
Utilize process enhancement opportunities to improve the efficiency of data pulling, reporting, programming and operations.
Support existing production pipelines
Troubleshoot and resolve issues as needed.
Identify, evaluate and apply new computational methodologies and emerging technologies to improve existing methods and tools.
Analyze genomics data in partnership with experimental and computational team members, industry partners and collaborators.
Perform literature reviews to learn about gold standard data analysis methods.
Write scripts, run analyses, visualize data and create figures for papers, presentations and posters.
Solve problems related to data analysis and troubleshoot and adapt published methodologies.
Prepare data for a variety of research projects.
Assist lab members, including graduate students and postdoctoral fellows, with training on bioinformatic tools.
Supervise and train trainees in their quantitative research projects.
Contribute to research protocols and grant proposals.
Perform other duties as assigned.
Bioinformatics Technologist
Minimum qualifications for the ideal future caregiver include:
Bachelor's Degree in Systems Biology, Bioinformatics, Computer Science or related field (such as Mathematics, Physics, Biology, Business Intelligence)
Ability to participate within a multidisciplinary team of IT professionals, physicians, molecular biologists, computer scientists, and biostatisticians
Possess knowledge of conducting data analytics, math or statistical modeling or machine learning
Experience in bioinformatics software
Detailed knowledge of core bioinformatics concepts and skills
Experience or willingness to learn R for specialized tasks and integration with data analytics workflows
Experience producing useful code (not necessarily in context of employment - personal projects or contributions to open-source projects are applicable)
Demonstrated experience in communication/presentation skills
Preferred qualifications for the ideal future caregiver include:
Proficiency in interpreted languages; Python or Perl
Experience with high-performance computing cluster
Experience analyzing high-throughput genomic, epigenomic and transcriptomic data (e.g., microarray data, next generation sequencing data) supported by published peer-reviewed studies
Knowledge of Microsoft Office (Word, Excel, Power Point and Outlook)
Bioinformatics Technologist II
Minimum qualifications for the ideal future caregiver include:
Bachelor’s degree in computer science/software engineering/bioinformatics or related field and three years of relevant experience
OR Master’s degree in a similar field and one year of relevant experience
Experience in DNA and RNA-seq data analysis
Solid understanding of all stages of software development cycle
Fluency in programming languages (Java, Python, Perl, R), UNIX shell scripts and database management systems (MySQL or PostgreSQL)
Experience with common bioinformatics tools (BWA, Bowtie, SAMtools, GATK, MuTect, VarScan, Strelka, STAR)
Proficiency with Linux/UNIX tools in high-performance computing clusters (HPC) environment
Excellent presentation and communication skills
Preferred qualifications for the ideal future caregiver include:
Experience with single-cell RNA sequencing data
Familiarity with agile software development approach
Experience with Cloud Computing
Experience analyzing high-throughput genomic, epigenomic and transcriptomic data (e.g., microarray data, next generation sequencing data) supported by published peer-reviewed studies
Knowledge of Microsoft Office (Word, Excel, Power Point and Outlook)
*The compensation range provided corresponds to the Bioinformatics Technologist I or Bioinformatics Technologist II position. Individual pay rates may vary depending on Education Background and Relevant Experience*
Physical Requirements:
Ability to perform work in a stationary position for extended periods.
Ability to travel throughout the hospital system.
Ability to operate a computer and other office equipment.
Ability to communicate and exchange accurate information.
Personal Protective Equipment:
Follows standard precautions using personal protective equipment.
The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.
Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.
Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.
If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/
Please review the Equal Employment Opportunity poster.
Cleveland Clinic is pleased to be an equal employment opportunity employer.